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Products / Stereotaxic Instruments

RWD Stereotaxic Instruments

Frames for neuroanatomy, neurophysiology, neuropharmacology and neurosurgery research. RWD stereotaxic instruments have been used in more than 5,000 published studies, including papers in Cell, Nature and Science.

Configurations for mice, rats, pigeons, cats, rabbits, dogs, monkeys and pigs, in three accuracy grades: 100 μm, 10 μm and 1 μm.

RWD desktop digital stereotaxic instrument with digital display

Choose by precision and animal

Except for the automated model 71000, every frame can be upgraded to a digital or dual-manipulator version later.

FamilyAccuracyAnimalsHighlights
Automated Stereotaxic Instrument1 μmMouse, ratSoftware control, built-in brain atlas, automated craniotomy, injection and tissue removal
Desktop Digital Stereotaxic Instrument10 μmMouse, ratLCD readout on every axis, one-key zero, battery powered
Standard Stereotaxic Instrument100 μmMouse, rat and other small animalsClassic U-frame, 80 mm working distance, double-lead screws
Portable Stereotaxic Instruments100 μm or 10 μmMouse; rat and mouseNo U-frame for more working space, adjustable nose and ear bar height
Large Animal Stereotaxic Instrument100 μm or 10 μmCat, dog, monkey, pigHolds up to six manipulator arms; MRI-compatible base available

Automated Stereotaxic Instrument

An automated, software-controlled frame with 1 μm accuracy. Built-in rat and mouse brain atlases show where the probe is in real time, and automated programs handle skull windows, tissue removal and injections. Anti-collision protection stops wrong movements before they reach the animal.

  • High-precision stepper motor: minimum displacement 0.33 μm
  • Anti-backlash compensation and user frame calibration
  • No leveling needed: four skull points set the tilt, and the atlas scales to the actual skull
  • Constant speed: 5 speeds on AP/ML, 9 on DV, down to 1 μm/s
  • Optional dual manipulators for bilateral targets in the same animal
RWD automated stereotaxic instrument with dual manipulators and laptop

Automated injection

Drives a nanoliter pump: 0.6–5000 nL at 0.02–200 nL/s, single or up to 10 points, with timed needle retention.

Tilted trajectories

Tilted craniotomy, injection or implantation without calculating three-axis offsets by hand.

Tissue removal kit

Automated aspiration (0–0.095 MPa) before GRIN lens implantation, for flatter surfaces and better miniscope imaging.

Automated craniotomy

Round or square cranial windows drilled under program control.

Slow withdrawal

Needle withdrawal as slow as 1 μm/s keeps virus or drug out of the needle tract.

3D view

Live display of position, layer count and implantation depth during the procedure.

Order information

ModelDescriptionNotes
71001-S / RS-SI*Automated Stereotaxic Instrument, SGL.M, Automatic InjectionLeft manipulator and nanoliter pump; laptop, adaptor, ear bars, holder and mask sold separately
71000-S / RS-S*Automated Stereotaxic Instrument, SGL.MLeft manipulator only
71001-D / RS-DI*Automated Stereotaxic Instrument, Dual.M, Automatic InjectionTwo manipulators and one nanoliter pump
71000-D / RS-D*Automated Stereotaxic Instrument, Dual.MTwo manipulators
71000-LTLaptop with control softwarei5-13420H / 16 GB / 512 GB / Windows 11 / 14"
71000-IInjection moduleNanoliter pump, cable, 3.5" and 7" glass capillaries, fittings, 68207 V-attachment
TRA-110 / TRA-220Tissue Removal Optional Kit (110 V / 220 V)Vacuum pump, reservoir, tubing, needle, connector and 68202 holder
78001MicrodrillFor craniotomy; use with 68605 holder and 78040 / 78042 drill bits
GC-3.5 / GC-7Glass capillary, 3.5" / 7"ID 0.53 mm, OD 1.14 mm

* RS- part numbers are designated for the U.S. market.

Desktop Digital Stereotaxic Instrument

The standard frame with a digital display module added. Displacement sensors read each axis to 10 μm, so there is no vernier to read and no arithmetic to do. The origin can be set anywhere in the travel range.

  • LCD readout of displacement in real time, 10 μm resolution
  • One key to zero, no second readings or calculations
  • AA battery powered, so no electrical interference with recordings
  • Works with anesthesia masks or anesthesia adaptors
RWD desktop digital stereotaxic instrument, dual manipulator
ModelDescriptionIncludes
68803Desktop Digital Stereotaxic Instrument, SGL M68861N base, 68409 digital manipulator (left)
68804Desktop Digital Stereotaxic Instrument, Dual M68861N base, 68409 left and 68410 right digital manipulators
68409 / 684103-Axis Digital Manipulator, Left / RightAdd 68410 to turn a single into a dual model

Standard Stereotaxic Instrument

The classic U-frame, in lab use for 20 years. 100 μm displacement accuracy; swap adaptors and ear bars to work with different small animals.

  • Working distance 80 mm, 100 μm reading accuracy
  • Wide Y-axis range, spacing up to 28 mm
  • Double-lead screws for smoother, more accurate motion
  • Separate vertical lock and positioning buttons keep the arm at exactly 90°
  • Extended base plate 400 × 255 mm; U-frame opening 115 mm; ear bar tip to base 51 mm
  • Upgradeable to digital (10 μm) or dual manipulators (add 68402)
RWD standard stereotaxic instrument with U-frame
ModelDescriptionIncludes
68801Standard Stereotaxic Instrument, SGL M68861N base, 68401 3-axis manipulator (left)
68802Standard Stereotaxic Instrument, Dual M68861N base, 68401 left and 68402 right manipulators
68861NStereotaxic Base Plate, Standard
68401 / 684023-Axis Manipulator, Left / Right

A complete setup = stereotaxic frame + adaptor + ear bars + holder, plus a nosecone mask for gas anesthesia. See the purchase guide.

Portable Stereotaxic Instruments

Portable frames drop the U-frame for more room around the animal. Non-digital models read to 100 μm, digital models to 10 μm.

RWD portable mouse stereotaxic instrument
Portable Mouse Stereotaxic InstrumentMouse-specific base for faster fixation. Nose bar and ear bar height adjust 0–20 mm; four ear bar fixing positions; 255 × 255 mm base.
RWD portable rat and mouse stereotaxic instrument
Portable Rat and Mouse Stereotaxic InstrumentRemovable adaptor and ear bars for rodents of different weights. Adaptor height 0–55 mm, ear bar height 0–45 mm.
ModelDescriptionAccuracy
68805Portable Mouse Stereotaxic Instrument, SGL M100 μm
68806Portable Mouse Stereotaxic Instrument, Dual M100 μm
68807Portable Mouse Stereotaxic Instrument, SGL M, Digital10 μm
68808Portable Mouse Stereotaxic Instrument, Dual M, Digital10 μm
68809Portable Rat and Mouse Stereotaxic Instrument, SGL M100 μm
68810Portable Rat and Mouse Stereotaxic Instrument, Dual M100 μm
68811Portable Rat and Mouse Stereotaxic Instrument, SGL M, Digital10 μm
68812Portable Rat and Mouse Stereotaxic Instrument, Dual M, Digital10 μm
68033Nose bar for 68030 mouse adaptor5 × 5 mm section
68313 / 6803445° / 18° ear bars for 68030 mouse adaptor5 × 5 mm section
68087 / 68088Mouse / rat adaptor for portable rat and mouse frames

Portable single-manipulator models can't be converted to dual by adding an arm. Contact us about an upgrade.

Large Animal Stereotaxic Instrument

For cats, dogs, monkeys and pigs. Two-dimensional (X, Z) manipulators; 100 μm non-digital or 10 μm digital.

  • Jaw plate design stabilizes heads across a wide weight range
  • Y-axis rail travel ±100 mm, 1 mm resolution
  • Vertical reading improves to 50 μm with a microdriver
  • Holds up to six manipulator arms
  • Adaptors: 68041 for animals under 10 kg, 68081 for 10–30 kg
RWD large animal stereotaxic instrument
ModelDescriptionIncludes
68813Stereotaxic for Large Animals, SGL M68868N base, 68941 2-axis manipulator (left)
68814Stereotaxic for Large Animals, Dual M68868N base, 68941 left and 68942 right manipulators
68815Stereotaxic for Large Animals, SGL M, Digital68868N base, 68944 digital manipulator (left)
68816Stereotaxic for Large Animals, Dual M, Digital68868N base, 68944 left and 68945 right digital manipulators

MRI Large Animal Stereotaxic Base (68915)

An all-plastic, MRI-compatible base for fixing the heads of 10–30 kg animals during MRI. Target brain regions from the scan, then position with a manipulator (sold separately; the manipulator is not MRI-compatible).

  • Base plate 420 × 200 mm; rails 19 × 19 mm, 325 mm long, 178.5 mm apart
  • Rail scale ±100 mm, 1 mm accuracy
  • Upper jaw plate: 80 mm front-back, 35 mm up-down; eye bar: 95 mm front-back
RWD MRI-compatible large animal stereotaxic base

Adaptors

Brain adaptors fit the standard, desktop digital and automated frames unless noted.

ModelDescription
68055Mouse Adaptor (head rotates 35°)
68030Mouse / Neonatal Rat Adaptor, 18° and 45° ear bars incl.
68057 / 68057-SMouse Anesthesia Adaptor, angle-adjustable ±35°, 20–30 g / 10–20 g
68077 / 68077-SMouse Anesthesia Adaptor, 20–30 g / 10–20 g
68065Rotational Mouse Adaptor, 60° ear bars incl.
68014Neonatal Mouse Adaptor (over 3 weeks), 20° and 45° ear bars
68072Neonatal Mouse Anesthesia Adaptor Kit (within 1 week)
68069MRI Compatible Mouse Adaptor
68021Rat Adaptor
68053Rat Anesthesia Adaptor, angle-adjustable, under 300 g
68078Rat Anesthesia Adaptor, under 300 g
68063Rotational Rat Adaptor, 18° ear bars
68011MRI Compatible Rat Adaptor
68022Rat Aural Adaptor (eye-socket fixation, hearing unobstructed)
68041Cat / Monkey Adaptor, under 10 kg
68081Dog / Monkey / Pig Adaptor, 10–30 kg
RWD mouse anesthesia adaptor

Spinal cord adaptors

  • 68091 Rat and Mouse Spinal Cord Adaptor, up to 500 g; three clamps, 56 mm vertical travel
  • 68094 Mouse Spinal Cord Adaptor, 20–30 g
  • 68095 Rat Spinal Cord Adaptor, 200–300 g

For 68041 and 68081, please send the animal's head width, nose-to-eye distance and mouth width before ordering so we can confirm fit with RWD.

Stereotaxic Anesthesia Nosecone Masks

Active masks must be used with a gas evacuation apparatus that pulls waste gas into a filter canister. Passive masks are used without one: waste gas flows into the canister on its own. See our waste gas products.

ModelTypeDescriptionCompatible adaptors
68663-SActiveAnesthesia/Evacuation Mask, mice or neonatal rats, 10–20 g68055, 68030, 68065, 68014, 68087
68663ActiveAnesthesia/Evacuation Mask, mice or neonatal rats, 20–30 g68055, 68030, 68065, 68087
68665ActiveAnesthesia/Evacuation Mask, mice or neonatal rats, 30–70 g68055, 68030, 68065, 68087
68666ActiveAnesthesia/Evacuation Mask, rats under 300 g68021, 68063, 68088
68667ActiveAnesthesia/Evacuation Mask, rats over 300 g68021, 68063, 68088
68601PassiveAnesthesia Mask Kit, mice or neonatal rats under 70 g, canister and tubing incl.68055, 68030, 68065, 68087
68602PassiveAnesthesia Mask Kit, rats under 300 g, canister and tubing incl.68021, 68063, 68088

Mouse masks include round and square (5 × 5 mm) incisor bars.

Ear Bars & Holders

Ear bars

  • 68306 Mouse 60° Ear Bars, obtuse tip to protect the skull
  • 68307 Mouse Serrated Ear Bars (hollow, large contact area)
  • 68308 Mouse O-shaped Ear Bars (rubber ring contact)
  • 68314 Mouse Height-Adjustable Serrated Ear Bars, −5 to +5 mm
  • 68301 / 68302 Rat 18° / 45° Ear Bars, 0.8 mm tip radius
  • 68305 Rat 45° Hollow Ear Bars for auditory stimulation
  • 68303 / 68304 Cat/Monkey 18° / 45° Ear Bars
  • 68413 Elevated Ear Bars, raise the head 50 mm

Holders

Every holder connects with the included 68207 V-attachment (8 mm rod) and also fits standard stereotaxic frames from other major brands. Pick by the diameter of what you need to clamp.

  • 68201 Standard Probe Holder, Corner: 0.3–1.5 mm
  • 68213 Standard Probe Holder, Side: 0.4–4.0 mm
  • 68210 / 68211 Electrode Holders: 0.7–2.5 / 2.1–5.0 mm
  • 68216 Electrode Holder: 0.4–1.5 mm (dual tips to 0.2 mm apart)
  • 68214 / 68215 Ceramic Ferrule Holders: 1.25 / 2.5 mm, for optogenetics
  • 68205 / 68230 / 68217 / 68221 Cannula Holders
  • 68202 / 68206 General Probe Holders: 6–12 / 3–12 mm
  • 68218 Syringe Holder; 68606 Manual Syringe Pump (1–1000 μL)
  • 68605 Microdrill Holder; 68106 Headstage Holder (0.1–7.0 mm)

Purchase guide

A complete setup is a stereotaxic frame, an adaptor, ear bars and a holder, plus a nosecone mask if you use gas anesthesia. Not sure? Send us your species and procedure and we'll put the configuration together.

Animal & experiment

Small animal (mouse, rat) or large animal (cat, dog, monkey, pig). Automated for calcium imaging, multi-point injection and craniotomy.

Accuracy

100 μm non-digital, 10 μm digital, or 1 μm automated.

Single or dual

Dual manipulators reach two brain regions of the same animal without re-zeroing.

Adaptor, ear bars, holder

Adaptor and ear bars by animal; holder by what you clamp.

Nosecone mask

Matched to the adaptor. Active masks need a gas evacuation apparatus.

Configure a stereotaxic system

Tell us the species, accuracy and procedure. We'll send a complete quote.

Request a Quote